There has been a lot of excitement recently about the potential relief from osteoarthritis (OA) one can gain from dietary nutritional supplements. These products are often called "nutriceuticals", a term used to explain benefits derived as being both nutrients and pharmaceuticals. In recent years, glucosamine and chondroitin, as well as naturally-occurring "good fats" have gained respect as pain relievers.
Nutritional supplements, however, have not proven to be any more effective in relieving pain than other remedies. Most studies contend that supplements are "just as effective" as certain pills for relieving OA symptoms. That in itself is good news.
Interestingly, we really don't know exactly how nutritional supplements relieve OA symptoms. Most of the compounds used in these supplements are found naturally in our bodies and are crucial to normal cartilage growth and repair. Different substances appear to work in different ways. So far, here's what the research suggests:
Glucosamine: Glucosamine is a mjor component of cartilage. It forms the building blocks for growth and maintenance of cartilage proteins. Remember that joint cartilage is 90% water - glucosamine absorbs water and keeps the joints lubricated. Taking supplements could promote the formation and repair of cartilage, perhaps slowing its deterioration and even preventing OA.
Chondroitin: Chondroitin is also found in your cartilage, bone and tendons. It is believed that chondroitin improves the durability of cartilage by helping its water retention and elasticity. It also appears that chondroitin can help block enzymes that can break down cartilage.
MSM and DMSO: MSM or methylsulfonylmethand (METH-ill-sul-FON-ill-METH-ane) and DMSO or dimethyl sulfoxide (DIE-meth-ill sul-FOX-ide) are related sulfur-containing organic liquids that are designed to relieve joint pain and inflammation. DSMO is a widely used commercial solvent, derived as a wood byproduct during the production of paper. Its many potential health benefits were first described in the early 1960's. It penetrates body tissues rapidly and is transformed into MSM in the body. These compounds quiet inflammation by scavenging free radicals released at the site of an injury, and keep swelling in check.
CM: CM or cetyl myristoleate (SEE-tull-meer-iss-TOLL-ee-ate) is a waxy fatty acid derived from beef tallow that seems to be an anti-inflammatory. Tests have shown that it prevents OA in laboratory mice.
Omega-3 "good fats": Omega-3 good fats come from fish such as salmon, mackerel, and tuna. A number of studies have supported their anti-infammatory effects as well.
There is also a wide range of other supplements, herbs, and oils that are believed to counteract inflammation. Certain foods are also linked with improving OA symptoms. The Arthritis Foundation is an excellent resource for reliable information about alternative and conventional therapies. You can find them online at www.arthritis.org.